Association of TSH level with first trimester pregnancy loss in anti-TPO antibody negative women in Bangladesh

Objective: To test if TSH level above 2.1 mlU/L is associated with first trimester pregnancy loss in anti-TPO antibody negative women in Bangladesh.

Study Design: An unmatched case-control study was conducted in Bangladesh. Patients were recruited following predefined inclusion and exclusion criteria. Clinical measures were taken as well as data on socioeconomic and physical characteristics were collected. Patients were grouped according to their TSH level—Group I with TSH ≤2.1 mlU/L and Group II with TSH > 2.1 mlU/L.

Results: We found relatively higher number of women in the case group (18) whose TSH level was above 2.1 mlU/L compared to 7 women in control group. In Group I 45.74% had lost pregnancy while 54.26% had continuing pregnancy during the first trimester. Among the Group II patients, 78% had miscarriage and 28% did not have miscarriage. The association between TSH level and first trimester pregnancy loss was statistically significant (p=.0196).In multivariate analysis, odds ratio for TSH level (OR 4.0, 95% CI: 1.44-11.16) indicates that odds of having miscarriage whose TSH level is above 2.1 mlU/L is 4 times compared to those with TSH level below 2.1 mlU/L after adjusting for the effects of age and BMI.

Conclusion: At a global level, the findings of this study provide evidence to the existing discussion on redefining the upper limit of TSH level that is related to first trimester pregnancy loss. At the local level, the results will have direct implication in facilitating management of future pregnancies particularly during the first trimester among Bangladeshi thyroid autoantibody negative women.

How to cite

Jahan Y, Raheem E, Akhteruzzaman M, Hussain MA, Kazal RK, et al. (2015) Association of TSH Level with First Trimester Pregnancy Loss in Anti-TPO Antibody Negative Women in Bangladesh. Med J Obstet Gynecol 3(3): 1061

Adaptation to climate change in coastal saline area of south-western region of Bangladesh


An adaptation research under Food and Agriculture Organization (FAO) funded LACC-II project started at coastal saline area of Laudove, Dakope upzila in Khulna district of Bangladesh through on-farm research division of Bangladesh Agricultural Research Institute (BARI), Khulna Bangladesh during May-June 2008 to May-June 2009. It aimed to find out the appropriate adaptation measures against salinity problem. After selection of adaptation options through three focus group discussions (FGD), homestead vegetable production started immediately with saline/excess soil moisture tolerant vegetables for coastal area. In coastal area several homestead vegetables were successfully produced through scientific management like making ridge and furrowing of bed. There was large participation of women in all the activities of home gardening from land preparation to marketing at Laudove. Through utilization of different niches of homestead farm family succeeded to increase their vegetable consumption three to five folds more from the bench mark, though intake was below recommended level. Economically homestead vegetable production was quite lucrative. Also social relationship of the farm family was improved with neighbors and relatives through free distribution of vegetables. Short duration T. aman rice variety (cv. BINAdhan 4) was tested at Laudove for facilitating timely planting of rabi crops. It gave better yield and one month shortening of field duration was possible. Farmers kept most of the produced seed for next year cultivation. In post-rainy season (Rabi) different field crops were tested, such as relaying (for timely planting and avoiding of increased soil salinity) of mustard, wheat, cowpea and later on creeping crops like watermelon and sweet gourd. Among them cowpea, water melon and sweet gourd proved to be promising.


Adaptation, Salinity, FGD, Vegetable and Short duration.

How to cite

Yusuf Ali, Shah AL-Emran, M. B. Islam, and E. Raheem (2014). Adaptation to climate change in coastal saline area of south-western region of Bangladesh. Int. J. Sustain. Agril. Tech. 10(4): 09-16, April 2014